Anna Karadimitrova was born in Sofia, Bulgaria.

She has been involved in music since childhood - she plays the piano and sings in the Children's Radio Choir. She graduated from the National Academy of Music "Prof. Pancho Vladigerov", after which she specialized at the European Opera Center in Manchester, UK. She is a laureate of the International singing competitions in Albena and Karlovy Vary, Czech Republic. From 1997 to 2000, she was a soloist at the Rousse Opera, where she made her debut in the role of Rosina in "The Barber of Seville" by Rossini. From 2000 to 2004 she was a freelance singer and participated in performances at the State Opera-Stara Zagora, the Operetta in Veliko Tarnovo, and at the Sofia stage in collaboration with the Sofia Philharmonic in Mozart's Requiem, Coronation Mass - Mozart, Magnificat by J.S. Bach within the framework of the European Music Festival and in chamber concerts. After 2004, she settled in Kuwait, where she engaged in vocal-pedagogical and choral-conducting activities. In parallel with teaching music, Anna Karadimitrova is a soloist in local chamber concerts with cantata-oratorio works, including "Gloria" by A. Vivaldi, "Carmina Burana" by K. Orff, Requiem by J. Verdi, "Gideon" by H. Bushman. She also participated in opera productions - "Don Juan", "Dido and Aeneas", "Semele", "The Pearl Fishers", "Acis and Galatea" and in operettas by Gilbert and Sullivan ("The Pirates of Penzance", "The Mikado", "The Gondoliers" and others), as well as in the musicals "West Side Story" and "Phantom of the Opera". In the summer of 2018 and 2019, she returned to the Bulgarian stage and participated in concerts at the Stara Zagora Opera. Recently, Anna was in the soloist composition of Requiem by Mozart - a joint production at the Kuwait Opera Center "Jaber Al Ahmad" with guest orchestra players and singers from Bulgaria. Currently, Anna Karadimitrova is part of the troupe of the State Opera Ruse. Anna Karadimitrova has had a certain interest in baroque music for years. She performed Handel's Messiah, Bach's Magnificat, Pergolesi's Stabat Mater, Vivaldi's Gloria, Semele's virtuoso soprano part in Handel's opera of the same name, the beautiful Galatea in Acis, and Galatea and the dramatic Dido in Purcell's Dido and Aeneas, etc.

In 1997-2000 she was a soloist of the Rousse Opera, where she debuted in the role of Rosina in Rossini's The Barber of Seville. From 2000 to 2004 she was a freelance singer and performed at the State Opera-Stara Zagora, the Operetta in Veliko Tarnovo and on the Sofia stage in collaboration with the Sofia Philharmonic in Mozart's Requiem, Mozart's Coronation Mass, Magnificat by J. С. Bach at the European Music Festival and in chamber concerts.

After 2004 he settled in Kuwait, where he was engaged in vocal pedagogical and choral conducting activities. Alongside teaching music, Anna Karadymitrova is a soloist in local chamber concerts with cantata-oratorio works, including "Gloria" by A. Vivaldi, "Carmina Burana" by K. Orff, Requiem by J. Verdi, "Gideon" by H. Buschmann. He has also participated in operatic productions - Don Giovanni, Dido and Aeneas, Semele, The Pearl Fishers, Acis and Galatea and in operettas by Gilbert and Sullivan (The Pirates of Penzance, The Mikado, The Gondoliers, etc.), as well as in the musicals West Side Story and The Phantom of the Opera.

In the summer of 2018 and 2019 he returns to the Bulgarian stage and performs in concerts of the Stara Zagora Opera. Most recently Anna was in the soloist line-up of Mozart's Requiem, a co-production at the Kuwait Jaber Al Ahmad Opera Centre with guest orchestrators and singers from Bulgaria.

At the moment Anna Karadimitrova is part of the troupe of State Opera-Ruse.

Anna Karadymitrova has had a certain interest in baroque music for years. She has performed Handel's Messiah, Bach's Magnificat, Pergolesi's Stabat Mater, Vivaldi's Gloria, the virtuoso soprano part of Semele in Handel's opera of the same name, the beautiful Galatea in Acis and Galatea and the dramatic Dido in Purcell's Dido and Aeneas, among others.